Overview
Requirements
Shipping
Genes
Overview
The Solid Tumor Profile is designed to analyze the molecular abnormalities in various solid tumors including cancers of the lung, pancreas, brain, colon, breast, ovary, endometrium, thyroid, head and neck, and soft tissue (sarcoma and GIST). The test provides physicians with clinically actionable information. This profiling covers abnormalities in single-nucleotide and indels in 434 genes. All exons of the 434 genes are covered and evaluated for abnormalities. In addition, the test is designed to detect microsatellite instability (MSI), tumor mutational burden (TMB) and homologous recombination deficiency (HRD). Significant amplification in various genes can also be detected and reported. The provided information helps in determining prognosis, design therapeutic approach and predict response to therapy.
Turn Around Time: 5-7 days
Requirements
- FFPE: 1 H&E slide and 6-8 unstained slides, 5-7 microns of tissue fixed with 10% NBF fixative. Please circle tumor for microdissection. Alternatively, the FFPE block can be sent for tumor circling and cutting at our laboratory.
- Complete requisition, making sure all sections are completed in their entirety including client information, patient Information, specimen Information and test selection. Missing information may delay reporting of test results.
- Diagnosis/patient history is extremely important in rendering the correct interpretation of results and should also be filled out as completely as possible.
- A copy of a path report should be included.
- Ensure the specimen is labeled with patient name and number. A minimum of two patient identifiers is required for each specimen.
Shipping
Specimen Preparation and Shipping Guidelines
Use Solid Tumor Transport Kit
- Complete Requisition, making sure all sections are completed in their entirety including client information, patient Information, specimen Information and test Selection. Missing information may delay reporting of test results.
- Diagnosis/patient history is extremely important in rendering the correct interpretation of results and should also be filled out as completely as possible. A copy of a Path report should be included.
- Ensure the specimen is labeled with patient name and number. A minimum of two patient identifiers is required for each specimen
For FFPE samples:
- If sending FFPE Block-Insert up to 6 blocks into plastic block tray provided. Insert block tray into foam insert in the transport box.
- If sending slides-Insert slides into plastic slide holders provided. Insert the slide holders into the foam insert in the transport box. The container will hold up to 6 maximum slide holders.
- Place folded test requisition(s) and/or manifest(s) if ordered electronically into the transport kit.
- Close box and tuck tabs into place. No tape necessary.
Genes
Genes validated and tested for Mutations in DNA testing for Solid Tumor
(* Microsatellite markers BAT25, BAT26, D2S123, D5S346, and D17S250 are included.)
How to complete
the Anthology Diagnostics requisition form.
Download our
Test Requisition
Keep in mind that we do not accept blood samples directly from individuals. Talk with your M.D. to fill out the form for you.