Solid Tumor Fusion/Expression Profile

Overview
Requirements
Shipping
Genes
Overview

The Solid Tumor Fusion/Expression Profile provides clinically relevant information on translocations and expression of cancer-specific genes. This assay is designed to detect various translocations involving more than 60 genes, including ALK, ROS1, RET, NTRK1, NTRK2, NTRK3, BRAF, CIC, EWSR1, PD-L1, and others. This also covers screening for sarcoma translocations and aids in sarcoma diagnosis and classification. In addition, the expression of genes of clinical relevance is reported including MYC, PD-L1, and others.

Turn Around Time: 7-10 days

Requirements

• FFPE: 1 H&E slide and 6-8 unstained slides, 5-7 microns of tissue fixed with 10% NBF fixative. Please circle tumor for microdissection. Alternatively, the FFPE block can be sent for tumor circling and cutting at our laboratory

Shipping

Specimen Preparation and Shipping Guidelines

Use Solid Tumor Transport Kit

• Complete Requisition, making sure all sections are completed in their entirety including client information, patient Information, specimen Information and test Selection.  Missing information may delay reporting of test results.
• Diagnosis/patient history is extremely important in rendering the correct interpretation of results and should also be filled out as completely as possible. A copy of a Path report should be included.
• Ensure the specimen is labeled with patient name and number.  A minimum of two patient identifiers is required for each specimen

For FFPE samples:

• If sending FFPE Block-Insert up to 6 blocks into plastic block tray provided. Insert block tray into foam insert in the transport box.
• If sending slides-Insert slides into plastic slide holders provided. Insert the slide holders into the foam insert in the transport box.  The container will hold up to 6 maximum slide holders.
• Place folded test requisition(s) and/or manifest(s) if ordered electronically into the transport kit. 
• Close box and tuck tabs into place. No tape necessary. 

Genes

Genes validated and tested for Mutations in DNA testing for Solid Tumor

How to complete
the Anthology Diagnostics requisition form.

Detailed Instructions

Download our
Test Requisition

Access Requisition

Keep in mind that we do not accept blood samples directly from individuals. Talk with your M.D. to fill out the form for you.

Do You Want to Download the Sample Report?

Sample Report for Solid Tumor Fusion/Expression Profile