Innovation in Next-Gen Sequencing
Making Genomic Testing Available and Affordable for Everyone
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Committed to driving the field of oncology diagnostics forward
Committed to driving the field of oncology diagnostics forward
Committed to driving the field of oncology diagnostics forward
Cancer is a complex disease requiring comprehensive answers. Only a comprehensive answer will allow medical professionals to make the highest quality care decisions for their patients.
At Anthology Diagnostics we analyze both DNA and RNA which gives the best possible answers based on our current knowledge.
Hackensack Meridian Health and Genomic Testing Cooperative (GTC) in Irvine, California, have teamed up to establish the first-of-its-kind genomic profiling laboratory called Anthology Diagnostics, to generate more personalized, precise, and real-time insights for cancer patients, oncologists and hospitals.
The reference laboratory (Anthology Diagnostics) located at Hackensack Meridian JFK University Medical Center in Edison, New Jersey will offer next generation sequencing data of DNA and RNA that is useful to clinicians in treatment decision-making for their patients as well as to researchers seeking to identify innovative biomarkers that can further improve the understanding and management of blood cancers and solid tumors.
GTC has developed highly validated tests for DNA as well as RNA profiling. DNA is the blueprint for all genetic information in the body; RNA converts genetic information from DNA to build proteins. Often in cancer, mutations in genes lead to defective proteins that can trigger cancer development, cause cancers to become resistant to treatment, or make them spread.
Profiling both DNA and RNA in a patient with cancer can provide more information than DNA testing alone regarding the cancer origin, biology, and clinical behavior as well as the response of the immune system of the patient to the cancer.
“We are thrilled with the launch of Anthology Diagnostics Laboratory as it demonstrates the commitment of Hackensack Meridian Health to enhance the diagnosis and treatment of cancer, which is one of the country’s most common illnesses and a leading cause of death in the United States,”
noted Robert C. Garrett, FACHE, chief executive officer, Hackensack Meridian Health. “The technologies we are spearheading with the laboratory puts us on the forefront of cancer care and research.”
“Paired DNA and RNA profiling is increasingly recognized as the new standard in precision medicine, and GTC is leading the way in the development of clinical applications for this approach. Although we are currently using genomic information for diagnostic and therapeutic decision-making, we have only touched the surface in terms of how this technology can be applied,”
said Andre Goy, M.D., physician-in-chief for Oncology at Hackensack Meridian Health.
“The collaboration between Hackensack Meridian Health and GTC will facilitate the translation of this technology to everyday patient care more quickly — not only at our institution, but along the entire East Coast.”
The results of next-generation genetic sequencing of DNA and RNA have enormous value for:
The Anthology Diagnostics lab will also be able to perform “liquid biopsies,” the analysis of cell-free DNA (cfDNA) released by cancer cells in the bloodstream.
Doctors can look for very early evidence of cancer just by taking a blood sample from a patient, avoiding the need for repeat invasive tissue biopsies in patients with solid tumors and bone marrow biopsies in those with hematologic (blood) cancers, such as leukemia.
“We look forward to collaborating with Hackensack Meridian Health through Anthology Diagnostics reference laboratory, which offers sophisticated high-quality molecular testing to strengthen the practice of precision medicine and drive innovation through research and development,”
explained Maher Albitar, M.D., chief executive officer and chief medical officer at GTC. “This collaboration will allow GTC to co-develop new tests with Hackensack Meridian Health utilizing real world clinical and outcomes data.”
The Anthology Diagnostics Laboratories at JFK University Medical Center complements the previously announced next-generation sequencing laboratory operated by Regional Cancer Care Associates (RCCA) in their practice at John Theurer Cancer Center at Hackensack University Medical Center, which provides services for RCCA physicians.
Physicians and hospitals interested in utilizing the services of Anthology Diagnostics laboratory at Hackensack Meridian JFK University Medical Center may contact 732-321-7240.
ABOUT HACKENSACK MERIDIAN HEALTH
Hackensack Meridian Health is a leading not-for-profit health care organization that is the largest, most comprehensive and truly integrated health care network in New Jersey, offering a complete range of medical services, innovative research and life-enhancing care.
Hackensack Meridian Health comprises 17 hospitals from Bergen to Ocean counties, which includes three academic medical centers:
two children’s hospitals:
nine community hospitals:
a behavioral health hospital: Carrier Clinic in Belle Mead;
and two rehabilitation hospitals:
Additionally, the network has more than 500 patient care locations throughout the state which include ambulatory care centers, surgery centers, home health services, long-term care and assisted living communities, ambulance services, lifesaving air medical transportation, fitness and wellness centers, rehabilitation centers, urgent care centers and physician practice locations.
Hackensack Meridian Health has more than 34,100 team members, and 6,500 physicians and is a distinguished leader in health care philanthropy, committed to the health and well-being of the communities it serves.
The Hackensack Meridian School of Medicine, the first private medical school in New Jersey in more than 50 years, welcomed its first class of students in 2018 to its campus in Nutley and Clifton.
Additionally, the network partnered with Memorial Sloan Kettering Cancer Center to find more cures for cancer faster while ensuring that patients have access to the highest quality, most individualized cancer care when and where they need it.
Hackensack Meridian Health is a member of AllSpire Health Partners, an interstate consortium of leading health systems, to focus on the sharing of best practices in clinical care and achieving efficiencies.
For additional information, please visit www.HackensackMeridianHealth.org.
About Genomic Testing Cooperative, LCA
Genomic Testing Cooperative (GTC) is a privately-owned molecular testing company located in Irvine, CA.
The company operates based on a cooperative (co-op) business model. Members of the co-op hold type A shares with voting rights. The company offers its patron members a full suite of comprehensive genomic profiling based mainly on next generation sequencing.
The co-op model allows GTC to make the testing and information platform available to members at a lower cost because of a lower overhead. For more information, please visit https://genomictestingcooperative.com/.
Both solid tumors (lung, colon, breast, etc) and hematologic malignancies (leukemia, multiple myeloma, etc) have molecular profiling tests available.
All major types of cancer have molecular testing that can be performed on them but the sample requirements will be different.
Solid Tumor
Detected Genes
Anthology Diagnostics was founded in partnership with Hackensack Meridian Health and Genomic Testing Cooperative to bring comprehensive genomic profiling for cancer to the local New Jersey community and east coast.
Anthology Diagnostics operates out of the JFK Medical Center and serves physicians, patients, hospitals and local labs to help advance precision medicine.
We provide tumor profiling for solid tumors and hematologic malignancies. Liquid biopsy testing is also available.
Anthology Diagnostics offers local state-of-the-art genomic profiling analyzing both DNA and RNA.
Our Precision Diagnostics offering utilizes the most advanced technology and software with deep learning to deliver advances in disease detection, prognosis and therapy recommendations. Our high-quality testing requires less tissue, provides faster results and is more cost efficient and affordable.
Anthology Diagnostics molecular profile tests are well validated and covered by Medicare and most major insurances.
Anthology Diagnostics is part of the Genomic Testing Cooperative network of laboratories.
GTC in collaboration with Anthology Diagnostics allows laboratories, health systems and Oncology groups to join this network, share resources, share knowledge, and collaborate in a community environment.
The GTC model produces big data for AI analysis creating value for hospitals, research, drug development, and others involved in cancer care.
Genomic sequencing revolutionary methods never used before. Next generation sequencing has changed medicine in the past decade in ways most people couldn’t imagine. It has allowed a rapid evolution to the field of precision medicine with new drugs being approved regularly.
Our AI helps us sort through curate large sets of data so we can quickly make sense of genomic alterations and assess their impact on a patient prognosis, diagnosis and help predict their response to therapy. We use machine learning to review these alterations and track their frequency.
Next generation sequencing has changed medicine in the past decade in ways most people couldn’t imagine. It has allowed a rapid evolution to the field of precision medicine with new drugs with being approved regularly.
However, it has previously been cost prohibitive with many insurance companies not covering testing. The data sets it produced were also hard to interpret and understand due to their size, complexity and lack of historical data.
At Anthology Diagnostics, we have now reached a time where we can utilize genomic testing in a cost-effective matter. The tools are now available to make sense of the complex data.
There is a large database of samples to look at and compare. In essence, we are at the tipping point of a deep understanding of cancer which we have never had before in human history and are making therapies that have the potential to cure the disease.
Cancer is a genomic disease and understanding what is happening at a genomic level helps medical professionals provide better care. Learn more about Anthology Diagnostics and dicuss with your physician for our tests.